Systems and methods for nasal support

ABSTRACT

Cartilage support implants for nasal valve support and delivery systems are described. The cartilage support implant can include one or more elongate bodies comprising one or more anchors. The cartilage support implant can be designed to be a permanent implant extending along the midline of a patient&#39;s nose, from the nasal bone to the lower lateral cartilage. Methods of placing the cartilage support implant and retrieving the cartilage support implant are also described.

PRIORITY CLAIM

This application is a divisional application of U.S. application Ser.No. 16/565,936 filed Sep. 10, 2019, which claims the benefit under 35U.S.C. § 119(e) as a nonprovisional application of U.S. Provisional App.No. 62/729,032 filed on Sep. 10, 2018, which is hereby incorporated byreference in its entirety. Any and all applications for which a foreignor domestic priority claim is identified in the Application Data Sheetas filed with the present application are hereby incorporated byreference under 37 CFR 1.57.

BACKGROUND Field

In some aspects, the invention relates generally to an implant for thetreatment of nasal valve collapse. Disclosed herein are systems andmethods for stabilizing the nasal valve including the use of a cartilagesupport implant.

Description of the Related Art

One cause of nasal airway obstruction is nasal valve collapse whichoccurs when the nasal cartilages fail to provide adequate support.During inspiration for heathy patients, the nasal cartilage functions tosupport the open nasal passages. The nasal cartilage limits or reducesvalve collapse. However, if the nasal cartilages become weakened, thenthe lateral nasal cartilages can collapse and obstruct the nasalairways. Collapse can be caused by various structures including but notlimited to the nasal septum, nasal turbinates, and lateral cartilages.

In many cases, there is a need to provide support to the nasalcartilages to prevent this collapse. There remains a need for improvedmethods and devices for treating various conditions, including but notlimited to nasal airway obstruction. There is also a need for improveddevices and methods for delivering and removing support structures fromthe cartilage. Specifically with respect to current methods forproviding support, there is a need to maintain support in the cartilage,provide sufficient anchoring for the support, improve the surgeon'srange and ability to precisely locate and orient the support includingany anchors, and improve the ability of surgeons to properly remove thesupport.

SUMMARY

The present disclosure provides cartilage support system as well asmethods for deploying and retrieving the cartilage support system.

In some embodiments, a system and method for supporting a nasal valve isprovided. The method can include providing a first elongate body and asecond elongate body sized to reside within the nose of a patient. Themethod can include placing the first elongate body adjacent to a firstnasal bone, wherein the first elongate body comprises a first anchor atan end of the first elongate body configured to be positioned closer tothe first nasal bone. The method can include placing the second elongatebody adjacent to a second nasal bone, wherein the second elongate bodycomprises a second anchor at an end of the second elongate bodyconfigured to be positioned closer to the second nasal bone. In someembodiments, the first elongate body and the second elongate body anchorwithin the nasal tissue and provide support to the nasal valve, whereinthe implant is made of biodegradable or bioresorbable material.

In some embodiments, the first anchor curves between about 5 and about360 degrees. In some embodiments, the second anchor curves between about5 and about 360 degrees. In some embodiments, the first elongate bodycomprises an additional anchor feature along the length of the firstelongate body. In some embodiments, the additional anchor featurecomprises a spike. In some embodiments, the implant is a stabilizingstent that extends between the nasal bone and the lower lateralcartilage. In some embodiments, the first elongate body is removable.The method can include engaging two anchors of each elongate body withthe anatomy of the patient. The method can include a single point ofanchoring. In some embodiments, the first elongate body includes acoating to promote tissue ingrowth. In some embodiments, the firstelongate body extends along the midline prominence of the nose. In someembodiments, the first elongate body is configured to be straightenedduring implantation within the nose of the patient. In some embodiments,the first elongate body is configured to be trimmed while straightened.

In some embodiments, a cartilage support implant is provided. Thecartilage support implant can include a first elongate body configuredto reside within the nose of a patient, the first elongate bodycomprising a first end comprising an anchor portion configured to have acompressed shape and an expanded shape, wherein the expanded shapecomprises a curved shape extending toward a second end of the elongatebody, opposite the first end, thereby forming a first anchor, theexpanded shape configured to anchor the first elongate body, In someembodiments, the implant is made of bioabsorbable material. In someembodiments, the first elongate body is configured to transition betweenthe expanded shape and the compressed shape.

In some embodiments, the first anchor curves between about 5 and 360degrees. In some embodiments, the expanded shape comprises a secondcurved shape extending toward a second end of the elongate body,opposite the first end, thereby forming a second anchor. In someembodiments, the first anchor curves between about 5 and 360 degrees,wherein the second anchor curves between about 5 and 360 degrees. Insome embodiments, the first elongate body comprises an additional anchorfeature along the length of the first elongate body. In someembodiments, the additional anchor feature comprises a spike. In someembodiments, the first elongate body is configured to be trimmed forlength when in the compressed shape.

BRIEF DESCRIPTION OF THE DRAWINGS

FIGS. 1A-1B illustrate a schematic view of the nasal passageways.

FIGS. 2A-2B illustrate an embodiment of a cartilage support implant.

FIGS. 3A-3E illustrate an embodiment of a cartilage support implant.

FIGS. 4-13 illustrate embodiments of a cartilage support implant.

FIGS. 14A-14C illustrate an embodiment of a cartilage support deliverysystem and a cartilage support implant.

FIGS. 15A-15L illustrate an embodiment of a cartilage support deliverysystem and a cartilage support implant.

FIGS. 16A-16I illustrate an embodiment of a cartilage support deliverysystem and a cartilage support implant.

DETAILED DESCRIPTION

FIG. 1A illustrates a side view of the structural anatomy of the nose.FIG. 1B is a front view. The nasal bones (NB) are illustrated. The nasalbones are two small, oblong bones that form the bridge of the nose. Theupper lateral cartilage (ULC) and the lower lateral cartilage (LLC) arealso illustrated. The upper lateral cartilage is situated below thenasal bone. The upper lateral cartilage has a flattened, triangularshape. The lower lateral cartilage is also known as the greater alarcartilage. The lower lateral cartilage is situated below the upperlateral cartilage. The upper lateral cartilage has a thin, flexibleplate shape, and is bent onto itself.

The nasal valve provides airflow resistance, which is important forpulmonary function. The nasal valve includes internal and externalportions. The external nasal valve dilates during inspiration and isformed by the columella, the nasal floor, and the lower lateralcartilage. The internal nasal valve provides greater resistance and istypically the narrowest part of the nasal passage. The internal nasalvalve is bounded by the septum, the upper lateral cartilage, and thepyriform aperture. The internal nasal valve is a segment between theseptum and the caudal margin of the upper lateral cartilage. The anglebetween the septum and the caudal margin of the upper lateral cartilageis typically between about 10 degree and 15 degrees. Collapse of theinternal nasal valve occurs when this angle is decreased.

The most common causes of nasal valve collapse include deviations of theseptum, trauma, deviations in the cartilage including twisted cartilageor the absence of cartilage, over-resection which weakens the cartilage,inflammation, and/or deformities in other structures including thepyriform aperture. Rhinoplasty is also known to damage the internalnasal valve. With nasal valve insufficiency, upon inspiratory efforts,the internal nasal valve collapses inwardly (medially) and obstructs thenasal airway.

A recent clinical study has shown that placing a bioresorbable stent orsplint across the upper lateral cartilage and the lower lateralcartilage and along the nasal bone can reduce symptoms of nasal valvecollapse. As a mechanical stabilizing structure, the benefits of thestent are reduced as it resorbs. Longer-lasting and more efficacioussystems and methods are needed.

FIGS. 2A-2B illustrate an embodiment of a cartilage support implant 100.The cartilage support implant 100 can function as a stabilizing stent.The cartilage support implant 100 can be a minimally invasiveimplantable stent that can be removable. The cartilage support implant100 can be non-bioresorbable, or bioresorbable in other embodiments. Thecartilage support implant 100 can provide sufficient support to reduceor prevent nasal valve collapse. The cartilage support implant 100 cancomprise a first elongate body 102 and a second elongate body 104. Insome embodiments, the first elongate body 102 and the second elongatebody 104 are substantially similar, similar, or identical. In someembodiments, the first elongate body 102 and the second elongate body104 are different. For instance, the first elongate body 102 and thesecond elongate body 104 can have one or more different dimensions, suchas length, width, height, or shape including cross-sectional shape, ormaterial. The elongate bodies could be discrete and unconnected asshown, or connected to one another in other embodiments.

Each elongate body 102, 104 can be sized to span between the upper nasalbone and the lower lateral cartilage. Each elongate body 102, 104 caninclude an upper portion configured to be placed near the nasal bone.Each elongate body 102, 104 can include a middle portion configured tobe placed near the upper lateral cartilage. Each elongate body 102, 104can include a lower portion configured to be placed near the lowerlateral cartilage. The elongate body 102, 104 can have any desiredcross-sectional shape (e.g., round, circular, elliptical, polygonal,rectangular, etc.). The elongate body 102, 104 can be solid. Theelongate body 102, 104 can be cannulated or tubular. The elongate body102, 104 can be rigid or flexible. The elongate body 102, 104 can beelastic or inelastic. The elongate body 102, 104 can be formed of one,two, or more materials. The elongate body 102, 104 can be formed from ametal, plastic, or any other biocompatible material.

The elongate bodies described herein can be formed from a bioresorbablematerial. The elongate body can be formed from a bioresorbable scaffold.The elongate body can be formed from a biodegradable material. Theelongate body can be formed from any naturally dissolving material. Theelongate body can be formed from any material that may dissolve or beabsorbed in the body. The elongate body can be formed from, for example,polylactic acid (PLLA), self-reinforced polylatic acid (SR PLLA),lactide and glycolide, polyglycolide or poly(glycolic acid) (PGA) and/orcombinations thereof. In some embodiments, the biodegradable orbioabsorbable material selected from the group consisting ofpolylactide, poly-L-lactide (PLLA), poly-D-lactide (PDLA), polyglycolide(PGA), polydioxanone, polycaprolactone, polygluconate, polylacticacid-polyethylene oxide copolymers, modified cellulose, collagen,poly(hydroxybutyrate), polyanhydride, polyphosphoester; poly(aminoacids), and poly(alpha-hydroxy acid). The elongate body can be formedfrom bioresorbable metals such as magnesium based metals or alloys, ormagnesium based metals or alloys, or zinc based metals or alloys. Allimplant embodiments can include a bioresorbable material option.

The elongate bodies described herein can be selected based on a lengthmeasurement. The user can determine the length of the implant based onmeasurements of the patient's anatomy. The length of the implant can bedetermined based on the length of the internal nasal valve. The lengthof the implant can be determined based on the length to the nasal bones.The length of the implant can be determined based on the length betweenthe upper nasal bone and the lower lateral cartilage. The length of theimplant can be determined based on the length of the upper lateralcartilage. The length of the implant can be determined based on anylandmarks within the nasal passage.

In some methods, the user selects an appropriate length implant to placein the delivery system for implantation. In some methods, the userselects an appropriate length implant based on the size of the implant.In some methods, the user selects an appropriate length implant based onthe shape of the implant. In some methods, the user selects anappropriate length implant based on the configuration of the anchors. Insome methods, the user select an appropriate length implant based on anevaluation of the patient's anatomy.

In some methods, the user selects an appropriate length implant bytrimming the implant to a desired length before delivery. In somemethods, the user straightens the implant in order to trim the implant.In some methods, the user trims the implant without straightening. Insome methods, the user bends the implant to change the length of theimplant. In some methods, the user straightens the implant to change thelength of the implant. In some methods, the user straightens the anchorsto change the length of the implant. In some methods, the user furthercurves the anchors to change the length of the implant.

In some methods, the user forms the implant before implantation. In somemethods, the implant arrives pre-formed to the user. In some methods,the implant is formed from a single length of material. In some methods,the implant is cut, trimmed, or otherwise reduced to an appropriatelength and/or other dimension before forming the implant shape. In somemethods, the implant is cut, trimmed, or otherwise reduced to anappropriate length after the implant shape is formed. In some methods,the elongate body is configured to transition between the expanded shapeand the compressed shape. In some methods, the elongate body isconfigured to be trimmed when in a compressed or straightened shape.

FIGS. 3A-3B illustrate an embodiment of a cartilage support implant 200.The cartilage support implant 200 comprises a first elongate body 202and a second elongate body 204. In some embodiments, the cartilagesupport implant 200 comprises only one elongate body. In someembodiments, the cartilage support implant 200 comprises a plurality ofelongate bodies (e.g., two, three, four, five, six, etc.). Each elongatebody 202, 204 can include a first end 206 configured to be placed nearthe nasal bone. Each elongate body 202, 204 can include a middle portion208 configured to be placed near the upper lateral cartilage. Eachelongate body 202, 204 can include a second end 210 configured to beplaced near the lower lateral cartilage. The first end 206 can includeone or more anchors, as describe herein.

FIG. 3C illustrates the first elongate body 202. FIG. 3D illustratesanother view of the first elongate body 202. The second elongate body204 can include any of the features of elongate body 202. The firstelongate body 202 can include a U-shaped configuration. The firstelongate body 202 includes a first strut 212 that extends the length ofthe elongate body 202. The elongate body 202 includes a second strut 214that extends the length of the elongate body 202. The elongate body 202can include a distal curve 216 that connects the first strut 212 and thesecond strut 214. The first strut 212 and the second strut 214 can lieon the same plane. The first strut 212, the distal curve 216, and thesecond strut 214 can lie on the same plane. The first strut 212 and thesecond strut 214 can be skewed. The distal curve 216 can twist such thatthe first strut 212 and the second strut 214 are skewed.

The first elongate body 202 can include a lower portion. The lowerportion can form a generally U-shape. The lower portion can include atleast one bend or curve. The lower portion can include the distal curve216. The first strut 212 can include a lower portion. The lower portionof the first strut 212 can extend from the distal curve 216. The secondstrut 214 can include a lower portion. The lower portion of the secondstrut 214 can extend from the distal curve 216. The lower portion of thefirst strut 212 and the second strut 214 can be parallel. The lowerportion of the first strut 212 and the second strut 214 can be skewed.The lower portion of the first strut 212 and the second strut 214 can bedisposed at an acute angle. The lower portion of the first strut 212 andthe second strut 214 can be generally straight. The lower portion of thefirst strut 212 and the second strut 214 can include a curve or a bend.

The first elongate body 202 can include an upper portion. The upperportion can form a generally T-shape. The upper portion can include atleast one bend or curve. The upper portion can include the first anchor222 and the second anchor 224. The first strut 212 can include an upperportion. The upper portion of the first strut 212 can extend outwardfrom the lower portion of the first strut 212. The second strut 214 caninclude an upper portion. The upper portion of the second strut 214 canextend outward from the lower portion of the second strut 214. The upperportion of the first strut 212 and the second strut 214 can be parallel.The upper portion of the first strut 212 and the second strut 214 can beskewed. The upper portion of the first strut 212 and the second strut214 can be disposed at an acute angle. The upper portion of the firststrut 212 and the second strut 214 can be generally curved. The upperportion of the first strut 212 and the second strut 214 can be the sameor similar. The upper portion of the first strut 212 and the secondstrut 214 can be mirror images.

The first anchor 222 can be formed from the proximal end of the firststrut 212 and the second anchor 224 can be formed from the proximal endof the second strut 214. In some embodiments, only the first strut 212forms the anchor 222. In some embodiments, only the second strut 214forms the anchor 224. The anchors 222, 224 form a rounded top surface ofeach strut 212, 214. The anchors 222, 224 can exert a biasing force onsurrounding structures, such as tissue, cartilage, and bone. The anchors222, 224 can resist movement of the elongate body. In some embodiments,the anchors 222, 224 penetrate the nasal bone. In some embodiments, theanchors 222, 224 do not penetrate the nasal bone. In some embodiments,positioning the anchors 222, 224 against the nasal bone provides enoughstability without penetrating the nasal bone. Each anchor 222, 224 canbe designed to engage a target location within the anatomical structure.

In some embodiments, the first anchor 222 extends below the first strut212, as shown in FIG. 3C. The first anchor 222 is coaxial with the firststrut 212. In some embodiments, the second anchor 224 extends below thesecond strut 214 as shown in FIG. 3C. The second anchor 224 is coaxialwith the second strut 214. In some embodiments, the first anchor 222extend above the first strut 212. The first anchor 222 is coaxial withthe first strut 212. In some embodiments, the second anchor 224 extendsbelow the second strut 214. The second anchor 224 is coaxial with thesecond strut 214. In some embodiments, the first anchor 222 and thefirst strut 212 lie generally within a first plane. In some embodiments,the second anchor 224 and the second strut 214 lie generally within asecond plane. In some embodiments, the first plane and the second planeare parallel.

In some embodiments, the first anchor 222 extends to the right from thefirst strut 212. The first anchor 222 is laterally offset with the firststrut 212. In some embodiments, the second anchor 224 extends to theleft of the second strut 214. The second anchor 224 is laterally offsetwith the second strut 214. In some embodiments, the first anchor 222,the second anchor 224, the first strut 212 and the second strut 214 liegenerally within the same plane.

In some embodiments, the first anchor 222 extends to the right anddownward from the first strut 212. The first anchor 222 is laterallyoffset and skewed with respect to the first strut 212. In someembodiments, the second anchor 224 extends to the left and downward ofthe second strut 214. The second anchor 224 is laterally offset andskewed with respect to the second strut 214. In some embodiments, thefirst anchor 222 and the first strut 212 lie generally within a firstplane. In some embodiments, the second anchor 224 and the second strut214 lie generally within a second plane. In some embodiments, the firstplane and the second plane are skewed.

In some embodiments, the first anchor 222 forms a curve. The firstanchor 222 can form a portion of a circle. The first anchor 222 cancurve between 5 and 360 degrees. The first anchor 222 can curve 5degrees, 10 degrees, 15 degrees, 20 degrees, 25 degrees, 30 degrees, 35degrees, 40 degrees, 45 degrees, 50 degrees, 55 degrees, 60 degrees, 65degrees, 70 degrees, 75 degrees, 80 degrees, 85 degrees, 90 degrees, 95degrees, 100 degrees, 105 degrees, 110 degrees, 115 degrees, 120degrees, 125 degrees, 130 degrees, 135 degrees, 140 degrees, 145degrees, 150 degrees, 155 degrees, 160 degrees, 165 degrees, 170degrees, 175 degrees, 180 degrees, 185 degrees, 190 degrees, 195degrees, 200 degrees, 205 degrees, 210 degrees, 215 degrees, 220degrees, 225 degrees, 230 degrees, 235 degrees, 240 degrees, 245degrees, 250 degrees, 255 degrees, 260 degrees, 265 degrees, 270degrees, 275 degrees, 280 degrees, 285 degrees, 290 degrees, 295degrees, 300 degrees, 305 degrees, 310 degrees, 315 degrees, 320degrees, 325 degrees, 330 degrees, 335 degrees, 340 degrees, 345degrees, 350 degrees, 355 degrees, 360 degrees, or any range of theforegoing values.

In some embodiments, the second anchor 224 forms a curve. The secondanchor 224 can form a portion of a circle. The second anchor 224 cancurve between 5 and 360 degrees. The first anchor 222 can curve 5degrees, 10 degrees, 15 degrees, 20 degrees, 25 degrees, 30 degrees, 35degrees, 40 degrees, 45 degrees, 50 degrees, 55 degrees, 60 degrees, 65degrees, 70 degrees, 75 degrees, 80 degrees, 85 degrees, 90 degrees, 95degrees, 100 degrees, 105 degrees, 110 degrees, 115 degrees, 120degrees, 125 degrees, 130 degrees, 135 degrees, 140 degrees, 145degrees, 150 degrees, 155 degrees, 160 degrees, 165 degrees, 170degrees, 175 degrees, 180 degrees, 185 degrees, 190 degrees, 195degrees, 200 degrees, 205 degrees, 210 degrees, 215 degrees, 220degrees, 225 degrees, 230 degrees, 235 degrees, 240 degrees, 245degrees, 250 degrees, 255 degrees, 260 degrees, 265 degrees, 270degrees, 275 degrees, 280 degrees, 285 degrees, 290 degrees, 295degrees, 300 degrees, 305 degrees, 310 degrees, 315 degrees, 320degrees, 325 degrees, 330 degrees, 335 degrees, 340 degrees, 345degrees, 350 degrees, 355 degrees, 360 degrees, or any range of theforegoing values.

FIG. 3E illustrates the first elongate body 202 with one or moreadditional anchoring features. The first strut 212 can include one ormore anchoring features 226. The second strut 214 can include one ormore anchoring features 228. In some embodiments, the anchoring features226, 228 are passive anchors. In some embodiments, the anchoringfeatures 226, 228 are spikes or barbs. In some embodiments, theanchoring features 226, 228 are wedges. In some embodiments, theanchoring features 226, 228 prevent movement in one direction but allowmovement in another direction.

In some embodiments, the anchoring features 226, 228 of the firstelongate body 202 are substantially similar, similar, or identical. Insome embodiments, the anchoring features 226, 228 of the first elongatebody 202 are different. For instance, the anchoring features 226, 228can have one or more different dimensions, such as length, width,height, or shape including cross-sectional shape, or material. Theanchoring features 226, 228 can be mirror image anchors. The anchoringfeatures 226, 228 can be symmetrical.

In some embodiments, the anchors 222, 224 of the first elongate body 202are substantially similar, similar, or identical. In some embodiments,the anchors 222, 224 of the first elongate body 202 are different. Forinstance, the anchors 222, 224 can have one or more differentdimensions, such as length, width, height, or shape includingcross-sectional shape, or material. The anchors 222, 224 can be mirrorimage anchors. The anchors 222, 224 can be symmetrical.

The anchor 222 can extend in a first direction away from the proximalend of the first strut 212, toward the distal curve 216, and in a seconddirection toward the first strut 212. The anchor 224 can extend in afirst direction away from the proximal end of the second strut 214,toward the distal curve 216, and in a second direction toward the secondstrut 214. Other configurations are contemplated. The anchors 222, 224can form a curve with a constant radius. The anchors 222, 224 can form acomplete curve. The anchors 222, 224 can form a helix. The anchors 222,224 can form an s-shaped curve. The anchors 222, 224 can form a u-shapedcurve. The anchors 222, 224 can form a j-shaped curve. In someembodiments, the elongate body 202 can be formed as a single piece. Theanchors 222, 224, the struts 212, 214, and the distal curve 216 can becontinuous.

The second elongate body 204 can include any of the features of thefirst elongate body 202 shown in FIG. 2B. The elongate body 204 caninclude a third strut 232, a fourth strut 234, and a distal curve 236.The elongate body 204 can include a third anchor 242 and a fourth anchor244. In some embodiments, the anchors 242, 244 of the second elongatebody 204 are substantially similar, similar, or identical. In someembodiments, the anchors 222, 224 of the first elongate body 202 and theanchors 242, 244 of the second elongate body 204 are substantiallysimilar, similar, or identical.

The elongate body 202, 204 can be formed from a metal, plastic, or anyother biocompatible material. The elongate body 202, 204 can beremovable, as described herein. The anchors 222, 224, 242, 244 caninclude a delivery configuration. The delivery configuration can be alow-profile configuration. For instance, the anchors 222, 224, 242, 244can be flattened or straightened for delivery. The anchors 222, 224,242, 244 can include a deployed configuration. The deployedconfiguration is shown in FIG. 3A-3B. The anchors 222, 224, 242, 244 canform a different shape than the delivery configuration. The anchors 222,224, 242, 244 can assume a pre-formed shape. In some embodiments, theanchors 222, 224, 242, 244 can comprise a shape memory material. Theanchors 222, 224, 242, 244 can include a pre-formed shape with at leastone curve. The anchors 222, 224, 242, 244 can be designed to provideattachment of the first elongate body 202 and the second elongate body204 to the respective nasal bones. The anchors 222, 224, 242, 244 cancomprise a nitinol alloy. The anchors 222, 224, 242, 244 can compriseany bio-inert material, such as any material typical of biologicalimplants, including stainless steel, titanium, and polymers such asPEEK. In some embodiments, the entire elongate body 202, 204 comprises anitinol alloy. In some embodiments, the anchors 222, 224, 242, 244 areself-expanding. In some embodiments, the anchors 222, 224, 242, 244 areremoved from a constraint and assume the deployed configuration. Theconstraint can be a delivery system such as a cannula or inserter, asdescribed herein.

In some embodiments, the anchors 222, 224, 242, 244 have apre-determined curved shape. The anchors 222, 224, 242, 244 can beformed of a shape memory material. The anchors 222, 224, 242, 244 can bedesigned to be spring-loaded. When delivered to the target location, theanchors 222, 224, 242, 244 can rapidly change shape from a low-profileor straightened shape to the pre-determined curved shape. In someembodiments, the anchors 222, 224 of the first elongate body 202 aredesigned to be deployed simultaneously. In some embodiments, the anchors242, 244 of the second elongate body 204 are designed to be deployedsimultaneously. In some embodiments, two or more anchors 222, 224, 242,244 are designed to be deployed simultaneously. In some embodiments, theanchors 222, 224 of the first elongate body 202 are designed to bedeployed separately or independently. In some embodiments, two or moreanchors 222, 224, 242, 244 are designed to be deployed separately orindependently.

Each elongate body 202, 204 can be a metallic or plastic removablestent. Each elongate body 202, 204 can include one or more anchors 222,224, 242, 244. The elongate body 202, 204 can be stabilized by the nasalbone. The material of the elongate body 202, 204, or a portion thereof,can include NiTi. The elongate body 202, 204, or a portion thereof, caninclude a circular cross-section. In some embodiments, each strut 212,214, 232, 234 can include a circular cross-section. The strut 212, 214,232, 234 can include in some embodiments a diameter or cross-sectionfrom about 0.008″ to about 0.020″ (e.g., 0.008″, 0.009″, 0.010″, 0.011″,0.012″, 0.013″, 0.014″, 0.015″, 0.016″, 0.017″, 0.018″, 0.019″ “, 0.020,between 0.005-0.015”, between 0.01-0.02″, between 0.015-0.025″, etc., orranges incorporating any two of the aforementioned values).

FIGS. 4-13 illustrate embodiments of cartilage support implants. In someembodiments, a cartilage support implant can comprise one elongate body.In some embodiments, a cartilage support implant can comprise twoelongate bodies. In some embodiments, a cartilage support implant cancomprise two elongate bodies that are similar, substantially similar oridentical. In some embodiments, a cartilage support implant can comprisetwo elongate bodies which are different (e.g., a combination of any twoelongate bodies describe herein). In some methods of use, the cartilagesupport implant is implanted relative to one nasal valve. In somemethods of use, the cartilage support implant comprises two elongatebodies which are implanted on opposite sides of the nasal structure asshown in FIGS. 2A-3B. Each elongate body can be implanted in a nasalvalve. The elongate bodies can be considered a right elongate body and aleft elongate body. The two elongate bodies can be the same orsubstantially similar. The two elongate bodies can be mirror images(e.g., opposite relative to a common axis). As one example, the anchorsof a first elongate body can extend in a first lateral direction, andthe anchors of a second elongate body can extend in a second, opposite,lateral direction. FIGS. 4-13 illustrate embodiments of an elongate bodyof a cartilage support implant. The elongate bodies of FIGS. 4-13 caninclude any of the features of elongate bodies of any cartilage supportimplant described herein.

FIG. 4 illustrates an elongate body 302 of a cartilage support implant300. The cartilage support implant 300 can include a plurality ofelongate bodies, as described herein. FIG. 4 illustrates a nasal valveimplant concept. The implant includes a support strut and offsetanchors. The implant is designed to engage tissue but allow implantremoval. The elongate body 302 can include a first end 306. In someembodiments, the first end 306 is configured to be placed near the nasalbone. The first end 306 can include one or more anchors, as describeherein. The elongate body 302 can include a middle portion 308. In someembodiments, the middle portion 308 is configured to be placed near theupper lateral cartilage. The elongate body 302 can include a second end310. In some embodiments, the second end 310 is configured to be placednear the lower lateral cartilage. Other methods of insertion arecontemplated.

The elongate body 302 can include a first strut 312 and a second strut314. The first strut 312 and the second strut 314 can be parallel. Thefirst strut 312 and a second strut 314 can be connected by a distalcurve 316 at the second end 310. The two struts 312, 314 can providesupport for the elongate body 302. The two struts 312, 314 can extendalong a common axis.

The first strut 312 can include a first anchor 322. The second strut 314can include a second anchor 324. Each strut 312, 314 can include ananchor 322, 324 at the first end 306. The anchors 322, 324 are offsetanchors. The anchors 322, 324 are offset from the common axis of the twoparallel struts 312, 314. The anchors 322, 324 can engage tissue butallow removal of the elongate body 302. The two parallel struts 312, 314can lie in a common plane. In some embodiments, the anchors 322, 324 donot contact the common plane. In some embodiments, the anchors 322, 324lie entirely on one side of the common plane.

The anchor 322 can extend in a first direction away from the first strut312, toward the second end 310, and in a second direction toward thefirst strut 312. The anchor 324 can extend in a first direction awayfrom the proximal end of the second strut 314, toward the second end310, and in a second direction toward the second strut 314. The anchors322, 324 curve back toward the second end 310. Upon insertion, theanchors 322, 324 curve back along the length of the elongate body 302.In some embodiments, the elongate body 302 can be formed as a unitaryimplant. The anchors 322, 324, the struts 312, 314, and the distal curve316 can be continuously connected.

FIG. 5 illustrates an elongate body 402 of a cartilage support implant400. The cartilage support implant 400 can include a plurality ofelongate bodies, as described herein. FIG. 5 illustrates a nasal valveimplant concept. The implant includes a support strut and centeredanchors. The elongate body 402 can include a first end 406. In someembodiments, the first end 406 is configured to be placed near the nasalbone. The first end 406 can include one or more anchors, as describeherein. The elongate body 402 can include a middle portion 408. In someembodiments, the middle portion 408 is configured to be placed near theupper lateral cartilage. The elongate body 402 can include a second end410. In some embodiments, the second end 410 is configured to be placednear the lower lateral cartilage.

The elongate body 402 can include a first strut 412 and a second strut414. The first strut 412 and the second strut 414 can be connected atthe second end 410 by a distal curve 416. The first strut 412 and thesecond strut 414 can be separated at the first end 406. In someembodiments, the struts 412, 414 extend the length of the elongate body402. In some embodiments, the struts 412, 414 extend a portion of thelength of the elongate body 402. In some embodiments, the struts 412,414 have a fixed distance therebetween at the second end 410. In someembodiments, the struts 412, 414 have a variable distance therebetweenat the first end 406. In some embodiments, the first end 406 of thestruts 412, 414 can flex toward and away from each other. In someembodiments, the first end 406 of the struts 412, 414 can flex in acommon plane. In some embodiments, the first end 406 of the struts 412,414 can flex to increase the distance therebetween at the first end 406.The two struts 412, 414 can provide axial rigidity for the elongate body402. The two parallel struts 412, 414 can resist extension.

The first strut 412 can include a first anchor 422. The second strut 414can include a second anchor 424. Each strut 412, 414 can include ananchor 422, 424 at the first end 406. The anchors 422, 424 are centeredanchors. The anchors 422, 424 are centered along a common axis of thestruts 412, 414. The two struts 412, 414 can lie in a common plane. Insome embodiments, the anchors 422, 424 are centered relative to thecommon plane. In some embodiments, the anchors 422, 424 lie equally onboth sides of the common plane. In some embodiments, each anchor 422,424 is centered relative to the longitudinal axis of the correspondingstrut 412, 424. In some embodiments, each anchor 422, 424 lies equallyon both sides of the longitudinal axis of the corresponding strut 412,414. In some embodiments, the longitudinal axis of the strut 412, 414extends through a midpoint of the corresponding anchor 422, 424.

The anchor 422 can extend clockwise from the end of the first strut 412.The anchor 422 can extend counterclockwise from the end of the firststrut 412. The anchor 424 can extend clockwise from the end of thesecond strut 414. The anchor 424 can extend counterclockwise from theend of the second strut 414. Each anchor 422, 424 can form a completecircle. Each anchor 422, 424 can form an enclosed perimeter. Each anchor422, 424 can form a closed shape. Each anchor 422, 424 can form anincomplete circle. Each anchor 422, 424 can form an open perimeter. Eachanchor 422, 424 can form an open shape. In some embodiments, theelongate body 402 can be monolithically formed. The anchors 422, 424,the struts 412, 414, and the distal curve 416 can form a single unit.

FIG. 6 illustrates an elongate body 502 of a cartilage support implant500. The cartilage support implant 500 can include a plurality ofelongate bodies, as described herein. FIG. 6 illustrates a nasal valveimplant concept. The implant includes a support strut and a nasal boneanchor. The implant includes expandable anchors. The implant includes atether hole. The implant can be formed from a molded plastic. Theelongate body 502 can include a first end 506. In some embodiments, thefirst end 506 is configured to be placed near the nasal bone. The firstend 506 can include one or more anchors, as describe herein. Theelongate body 502 can include a middle portion 508. In some embodiments,the middle portion 508 is configured to be placed near the upper lateralcartilage. The elongate body 502 can include a second end 510. In someembodiments, the second end 510 is configured to be placed near thelower lateral cartilage.

The elongate body 502 can include a support strut 512 extending betweenthe first end 506 and the second end 510. The elongate body 502 caninclude a connection point 526 at the second end 510. The connectionpoint 526 can include an aperture 528 designed to accept a tether (notshown). Other connection points are contemplated. The connection point526 can include an elongated slot or a round hole. The connection point526 can include a threaded bore. The connection point 526 can include ahook. The connection point 526 can include a fastener. The connectionpoint 526 can be integrally molded with a tether. The connection point526 can include an adhesive. The connection point 526 can include amechanical connection. The connection point 526 can include a snap. Theconnection point 526 can form a rounded distal surface of the elongatebody 502.

The elongate body 502 can include an anchor 522 at the first end 506.The anchor 522 can be designed to engage the nasal bone. The anchor 522can form a complete circle. The anchor 522 can form an enclosedperimeter. The anchor 522 can form a closed shape. The anchor 522 canform a rounded proximal surface of the elongate body 502. The anchor 522can be designed to abut, but not penetrate, tissue surrounding the nasalbone.

The elongate body 502 can include one or more middle anchors. Theelongate body 502 can include a first middle anchor 552 and a secondmiddle anchor 554. The middle anchors 552, 554 can be designed to engagetissue along the length of the elongate body 502. The anchors 552, 554can be designed to engage the upper lateral cartilage. The 552, 554 canbe disposed in the middle portion 508 of the elongate body 502. Theanchors 552, 554 can include one or more barbs to engage tissue. In someembodiments, the anchors 552, 554 can be fixed in position. The anchors552, 554 can be flexible or rigid.

In some embodiments, the anchors 552, 554 can be expandable. Theelongate body 502 can include a central axis. The anchors 552, 554 canexpand outward from the central axis. The anchors 552, 554 can expandlaterally. The anchors 552, 554 can expand in opposite directions. Theanchors 552, 554 can be mirror image anchors. In some embodiments, theanchors 552, 554 can expand from the same location along the length ofthe elongate body 502. In some embodiments, the anchors 552, 554 canexpand from different locations along the length of the elongate body502.

The anchors 552, 554 can include a low-profile or compressedconfiguration. For instance, the anchors 552, 554 can be flattened orstraightened for delivery. In the compressed configuration, the elongatebody 502 can have a first cross-sectional shape. The anchors 552, 554can include an expanded configuration. The anchors 552, 554 can assume apre-formed shape. In the expanded configuration, the elongate body 502can have a second cross-sectional shape. The second cross-sectionalshape can be larger than the first cross-sectional shape (e.g., 10%larger, 20% larger, 30% larger, 40% larger, 50% larger, 60% larger, 70%larger, 80% larger, 90% larger, 100% larger, 200% larger, etc.). Theelongate body 502 can be formed from any biocompatible material. Theelongate body 502, or a portion thereof, can be formed from a moldedplastic. In some embodiments, the anchors 552, 554 are formed of adifferent material than another portion of the elongate body 502.

FIG. 7 illustrates an elongate body 602 of a cartilage support implant600. The cartilage support implant 600 can include a plurality ofelongate bodies, as described herein. FIG. 7 illustrates a zigzagpattern which provides anchoring. The implant can include a tether hole.The elongate body 602 can include a first end 606. In some embodiments,the first end 606 is configured to be placed near the nasal bone. Theelongate body 602 can include a middle portion 608. In some embodiments,the middle portion 608 is configured to be placed near the upper lateralcartilage. The elongate body 602 can include a second end 610. In someembodiments, the second end 610 configured to be placed near the lowerlateral cartilage.

The elongate body 602 can include a support strut 612 extending betweena first end 606 and a second end 610. The elongate body 602 can includea connection point 626 at the second end 610. The connection point 626can include a tether hole or other connection point, as describedherein. The elongate body 602 can include a zig-zag pattern. The zig-zagpattern of the elongate body 602 provides anchoring. In someembodiments, the elongate body 602 does not have a central axis. Thezig-zag pattern of the elongate body 602 can be a regular pattern ofrepeating line segments. The zig-zag pattern of the elongate body 602can include segments of the same length. The zig-zag pattern of theelongate body 602 can include segments of two or more different lengths.The zig-zag pattern of the elongate body 602 can be an irregular patternof repeating line segments.

FIG. 8 illustrates an elongate body 702 of a cartilage support implant700. The cartilage support implant 700 can include a plurality ofelongate bodies, as described herein. FIG. 8 illustrates a nasal valveimplant concept. The implant can include a molded plastic stiffener. Theimplant can include NiTi. The implant can include an anchor. The implantcan include a tether hole. The elongate body 702 can include a first end706. In some embodiments, the first end 706 is configured to be placednear the nasal bone. The first end 706 can include one or more anchors,as describe herein. The elongate body 702 can include a middle portion708. In some embodiments, the middle portion 708 is configured to beplaced near the upper lateral cartilage. The elongate body 702 caninclude a second end 710. In some embodiments, the second end 710 isconfigured to be placed near the lower lateral cartilage.

The elongate body 702 can include a strut 712. The strut 712 can providesupport for the elongate body 710. The strut 712 can have a centrallongitudinal axis. The strut 712 can include an anchor 722. The anchor722 can be an offset anchor. The anchor 722 is offset from the centrallongitudinal axis of the strut 712. The offset shape of the anchor 722can easily engage tissue but also allow for removal of the elongate body702, if needed. The anchor 722 can extend downward and away from thestrut 712 and then curve back toward the strut 712.

The strut 712 and/or the anchor 722 can include a shape memory material.In some embodiments, the strut 712 and/or the anchor 722 can compriseNiTi. The elongate body 702 can include a sleeve 718. The sleeve 718 canbe a coating. The sleeve 718 can surround at least a portion of thestrut 712. The sleeve 718 can surround at least a portion of the lengthof the strut 712. The sleeve 718 can surround at least a portion of thecircumference of the strut 712. The sleeve 718 can include a polymer. Insome embodiments, the sleeve 718 can comprise a material that is stifferthan the strut 712. In some embodiments, the sleeve 718 can provideadded rigidity to the strut 712. In some embodiments, the sleeve 718 isfixed related to the strut 712. The sleeve 718 can be molded onto thestrut 712. The sleeve 718 can fully encircle the strut 712 or partiallyencircle the strut 712. The sleeve 718 can encase the entire length ofthe strut 712, or a portion thereof. In some embodiments, the sleeve 718is removable. The sleeve 718 can be disposed within or near the middleportion 708 of the elongate body 702.

The elongate body 702 can include a connection point 726. The connectionpoint 726 can include an aperture 728 designed to accept a tether. Theconnection point 726 can be at the opposite end of the elongate body 702as the anchor 722. The connection point 726 can extend clockwise fromthe strut 712. The connection point 726 can extend counterclockwise fromthe strut 712. The anchor 722 can extend clockwise from the strut 712.The anchor 722 can extend counterclockwise from the strut 712. Theconnection point 726 and the anchor 722 can extend in oppositedirection.

The anchor 722 and/or the connection point 726 can form a complete ornearly complete circle. The anchor 722 and/or the connection point 726can form an enclosed perimeter or other closed shape. The closed shapemay facilitate retention of the tether within the connection point 726.The anchor 722 and/or the connection point 726 can form an incompletecircle. The anchor 722 and/or the connection point 726 can form an openperimeter or other open shapes. The open shape may facilitate removal ofthe anchor 722 from the surrounding tissue, cartilage, or bone. In someembodiments, the elongate body 702 can be integrally formed. The anchor722, the strut 712, and the connection point 726 can form a continuousstructure.

FIG. 9 illustrates an elongate body 802 of a cartilage support implant800. The cartilage support implant 800 can include a plurality ofelongate bodies, as described herein. FIG. 9 illustrates a nasal valveimplant concept. The implant can include an elongate body laser cut fromplastic or metal sheet. The implant can be molded. The implant caninclude anchor features. The implant can include variable widths foranchoring. The elongate body 802 can include a first end 806. In someembodiments, the first end 806 is configured to be placed near the nasalbone. The first end 806 can include one or more anchors or anchorfeatures, as describe herein. The elongate body 802 can include a middleportion 808. In some embodiments, the middle portion 808 configured tobe placed near the upper lateral cartilage. The elongate body 802 caninclude a second end 810. In some embodiments, the second end 810 isconfigured to be placed near the lower lateral cartilage. The second end810 can include a connection point 826.

The elongate body 802 can include a strut 812. The strut 812 can includean anchor 822. The anchor 822 can be a bifurcated anchor. The anchor 822can include one or more barbs. In FIG. 9 , the anchor 822 includes twobarbs but other configurations are contemplated (e.g., one barb, twobarbs, three barbs, four barb, five barbs, six barbs, etc.). The barbscan extend outward from a central axis of the elongate body 802. Thebarbs can be designed to engage tissue, bone, or cartilage. In someembodiments, the barbs curve from the first end 806 toward the secondend 810.

The elongate body 802 can include one or more middle extensions. Theelongate body 802 can include a first middle extension 862 and a secondmiddle extension 864. The middle extensions 862, 864 can be designed toengage tissue along the length of the elongate body 802. The extensions862, 864 can be designed to engage the upper lateral cartilage. Theextensions 862, 864 can be disposed in the middle portion 808 of theelongate body 802. The extensions 862, 864 can increase a dimension ofthe elongate body 802. The extensions 862, 864 can increase a width orthickness of the elongate body 802. In some embodiments, the extensions862, 864 can be fixed in position. The extensions 862, 864 can beflexible or rigid. The extensions 862, 864 can improve anchoring of theelongate body 802. The extensions 862, 864 can be located in the middleportion 808 of the elongate body 802.

In some embodiments, the extensions 862, 864 can be expandable. Theelongate body 802 can include a longitudinal axis. The extensions 862,864 can expand outward from the longitudinal axis. The extensions 862,864 can expand laterally. The extensions 862, 864 can expand in oppositedirections. The extensions 862, 864 can be mirror image of each other.In some embodiments, the extensions 862, 864 can expand from the samelocation along the length of the elongate body 802. In some embodiments,the extensions 862, 864 can expand from different locations along thelength of the elongate body 802. There can also be an aperture betweenextensions 862, 864 as shown.

FIG. 10 illustrates an elongate body 902 of a cartilage support implant900. The cartilage support implant 900 can include a plurality ofelongate bodies, as described herein. FIG. 10 illustrates a nasal valveimplant concept. The implant can include an anchor. The implant caninclude two anchors which are offset from each other. The implant caninclude ePTFE or polyester for tissue ingrowth for long term stability.The anchor can be formed of NiTi or super-elastic wire. The anchor canbe laser cut. The anchor can be plastic molded. The elongate body 902can include a first end 906. In some embodiments, the first end 906 isconfigured to be placed near the nasal bone. The first end 906 caninclude one or more anchors, as describe herein. The elongate body 902can include a middle portion 908. In some embodiments, the middleportion 908 is configured to be placed near the upper lateral cartilage.The elongate body 902 can include a second end 910. In some embodiments,the second end 910 configured to be placed near the lower lateralcartilage.

The elongate body 902 can include a first strut 912 and a second strut914. The first strut 912 and a second strut 914 can be connected by adistal curve 916 at the second end 910. The first strut 912 and thesecond strut 914 can extend from the distal curve 916 and be parallel.The first strut 912 and the second strut 914 can extend from the distalcurve 916 and be skewed. The first strut 912 and the second strut 914can be separated along the length of the elongate body 902. The twostruts 912, 914 can provide support for the elongate body 902. The twostruts 912, 914 can be separated at the first end 906. The two struts912, 914 can be able to flex toward and away from each other at thefirst end 906.

The first strut 912 can include a first anchor 922. The second strut 914can include a second anchor 924. Each strut 912, 914 can include ananchor 922, 924 at the first end 910. The anchors 922, 924 are offsetanchors. The anchors 922, 924 extend below the plane containing thestruts 912, 914. The anchors 922, 924 extend downward from the struts912, 914 and curve backward toward the second end 910. The anchors 922,924 can engage tissue, bone, or cartilage. The shape of the anchors 922,924 can allow for removal of the elongate body 902.

The struts 912, 914 and/or the anchors 922, 924 can include a shapememory material. In some embodiments, the struts 912, 914 and/or theanchors 922, 924 can comprise NiTi. The elongate body 902 can include asleeve 918. The sleeve 918 can be designed to surround at least aportion of the elongate body 902. The sleeve 918 can be designed tosurround the middle portion 908. The distal curve 916 and the sleeve 918can form a connection point 926. The distal curve 916 and the sleeve 918can form an enclosed aperture 928. The sleeve 918 can provide supportfor the struts 912, 914. The sleeve 918 can reduce the flexibility ordegree of motion of the struts 912, 914. The sleeve 918 can include apolymer. The sleeve 918 can include ePTFE, polyester, and/or any plasticor plastic-like material. The sleeve 918 can include a material suitablefor tissue ingrowth. The sleeve 918 can include bone graft material. Thesleeve 918 can include bone cement. The sleeve 918 can include a matrixincluding bone growth factors. The sleeve 918 can promote tissueingrowth for permanent installation of the implant. In some embodiments,the elongate body 902 can be formed as a continuous single wire. Theanchors 922, 924, the struts 912, 914, and the distal curve 916 can beintegrally formed as a single structure.

FIG. 11 illustrates an elongate body 1002 of a cartilage support implant1000. The cartilage support implant 1000 can include a plurality ofelongate bodies, as described herein. FIG. 11 illustrates a nasal valveimplant concept. The implant can include a tether hole. The implant caninclude prolapsable anchors to allow removal. The elongate body 1002 caninclude a first end 1006. In some embodiments, the first end 1006 isconfigured to be placed near the nasal bone. The elongate body 1002 caninclude a middle portion 1008. In some embodiments, the middle portion1008 is configured to be placed near the upper lateral cartilage. Theelongate body 1002 can include a second end 1010. In some embodiments,the second end 1010 is configured to be placed near the lower lateralcartilage. The elongate body 1002 can include a connection point 1026including any of the features described herein.

The elongate body 1002 can include one or more middle anchors, such asbarbs extending radially outwardly both sides of the device, or only oneside in other embodiments. The elongate body 1002 can include a firstset of middle anchors 1052 and a second set of middle anchors 1054. Themiddle anchors 1052, 1054 can be designed to engage tissue along thelength of the elongate body 1002. The middle anchors 1052, 1054 can bedesigned to engage the upper lateral cartilage. The middle anchors 1052,1054 can be disposed in the middle portion 1008 of the elongate body1002. The middle anchors 1052, 1054 can include one or more barbs toengage tissue. In some embodiments, the middle anchors 1052, 1054 can befixed in position. The middle anchors 1052, 1054 can be flexible orrigid. In some embodiments, the middle anchors 1052, 1054 can beexpandable. The elongate body 1002 can include a central axis. Themiddle anchors 1052, 1054 can expand outward from the central axis. Themiddle anchors 1052, 1054 can expand laterally.

The first set of middle anchors 1052 can expand in an opposite directionas the second set of middle anchors 1054. The first set of middleanchors 1052 can expand in a first direction. The second set of middleanchors 1054 can expand in a second direction, opposite the firstdirection. The first set of middle anchors 1052 can be disposed near thefirst end 1006. The first set of middle anchors 1052 can point towardthe first end 1006. The second set of middle anchors 1054 can bedisposed near the second end 1010. The second set of middle anchors 1054can point toward the second end 1008. The first set of middle anchors1052 can be considered unidirectional anchors. The second set of middleanchors 1054 can be considered unidirectional anchors.

In some embodiments, two or more anchors from the first set of middleanchors 1052 can expand from the same location along the length of theelongate body 1002 In some embodiments, two or more anchors from thesecond set of middle anchors 1054 can expand from the same locationalong the length of the elongate body 1002. In some embodiments, two ormore anchors of the middle anchors 1052, 1054 can expand from differentlocations along the length of the elongate body 1002. The first set ofmiddle anchors 1052 can be retracted to allow for removal of theelongate body 1002. The second set of middle anchors 1054 can beretracted to allow for removal of the elongate body 1002.

FIG. 12 illustrates an elongate body 1102 of a cartilage support implant1100. The cartilage support implant 1100 can include a plurality ofelongate bodies, as described herein. FIG. 12 illustrates a nasal valveimplant concept. The elongate body 1102 can include a first end 1106. Insome embodiments, the first end 1106 is configured to be placed near thenasal bone. The elongate body 1102 can include a middle portion 1108. Insome embodiments, the middle portion 1108 is configured to be placednear the upper lateral cartilage. The elongate body 1102 can include asecond end 1110. In some embodiments, the second end 1110 configured tobe placed near the lower lateral cartilage. The elongate body 1102 caninclude a connection point 1126 as described herein.

The elongate body 1102 can include one or more middle anchors. Theelongate body 1102 can include a first middle anchor 1152 and a secondmiddle anchor 1154. The middle anchors 1152, 1154 can be disposed in themiddle portion 1108 of the elongate body 1102. The middle anchors 1152,1154 can include one or more barbs to engage tissue. In someembodiments, the middle anchors 1152, 1154 can be expandable. In someembodiments, the middle anchors 1152, 1154 can be retractable. The firstmiddle anchor 1152 can expand in an opposite direction as the secondmiddle anchor 1154. The first middle anchor 1152 can expand in a firstdirection. The second middle anchor 1154 can expand in a seconddirection, opposite the first direction. The anchors 1152, 1154 canincrease the width of the cartilage support implant 1100.

FIG. 13 illustrates an elongate body 1202 of a cartilage support implant1200. The cartilage support implant 1200 can include a plurality ofelongate bodies, as described herein. FIG. 13 illustrates a nasal valveimplant concept. The implant can include no more than a single distaltine, or two or more tines in other embodiments. The implant can includea tether loop. The implant can include a mesh or solid coating. Theimplant can include an anchor. The elongate body 1202 can include afirst end 1206. In some embodiments, the first end 1206 is configured tobe placed near the nasal bone. The first end 1206 can include one ormore anchors, as describe herein. The elongate body 1202 can include amiddle portion 1208. In some embodiments, the middle portion 1208 isconfigured to be placed near the upper lateral cartilage. The elongatebody 1202 can include a second end 1210. In some embodiments, the secondend 1210 is configured to be placed near the lower lateral cartilage.

The elongate body 1202 can include a strut 1212. The strut 1212 canprovide support for the elongate body 1202. The strut 1212 can include adistal curve 1216. The distal curve 1216 can curve from the second end1210 toward the first end 1206. The strut 1212 can have a centrallongitudinal axis. The strut 1212 can include an anchor 1222. The anchor1222 can be a centered anchor.

The anchor 1222 can be centered along a longitudinal axis of the strut1212. The anchor 1222 can be centered relative to the longitudinal axisof the strut 1212. In some embodiments, the anchor 1222 lies equallyabove and below the longitudinal axis. In some embodiments, thelongitudinal axis of the strut 1212 extends through a midpoint of theanchor 1222. The anchor 1222 can form a complete or nearly completecircle. The anchor 1222 can form an incomplete circle. The anchor 1222can form an open perimeter or other open shapes. The open shape mayfacilitate removal of the anchor 1222 from the surrounding tissue,cartilage, or bone.

The elongate body 1202 can include a connection point 1226. Theconnection point 1226 can include an aperture 1228 designed to accept atether. The connection point 1226 can be at the opposite end of theelongate body 1202 as the anchor 1222. The connection point 1226 canextend counterclockwise from the strut 1212. The anchor 1222 can extendclockwise from the strut 1212. The connection point 1226 and the anchor1222 can extend in opposite direction. The connection point 1226 canform an enclosed perimeter or other closed shape. The closed shape mayfacilitate retention of the tether within the connection point 1226.

The strut 1212 and/or the anchors 1222 can include a shape memorymaterial. In some embodiments, the strut 1212 and/or the anchors 1222can comprise NiTi. The elongate body 1202 can include a sleeve 1218. Thesleeve 1218 can be designed to surround at least a portion of theelongate body 1202. The sleeve 1218 can be designed to surround themiddle portion 1208.

The distal curve 1216 and the sleeve 1218 can form the connection point1226. The distal curve 1216 and the sleeve 1218 can form an enclosedspace. The sleeve 1218 can form a connection between two segments of thedistal curve 1216 and/or the strut 1212. The sleeve 1218 can providesupport for the strut 1212. The sleeve 1218 can include a mesh. Thesleeve 1218 can include a solid coating. The sleeve 1218 can promotetissue ingrowth. In some embodiments, the elongate body 1202 can beformed as a continuous structure. The anchor 1222, the strut 1212, andthe distal curve 1216 can be formed from the same material.

FIGS. 14A-14C illustrate an embodiment of a cartilage support deliverysystem 1300 for a cartilage support implant. The cartilage supportdelivery system 1300 can be designed to delivery any cartilage supportimplant described herein. In some embodiments, the cartilage supportdelivery system 1300 delivers one elongate body at a time. In someembodiments, the cartilage support delivery system 1300 delivers two ormore elongate body simultaneously.

FIGS. 14A-14C illustrate a delivery system for the nasal valve implant.The delivery system 1300 can include a cannula 1302. The cannula 1302can be hollow. The cannula 1302 can be designed to accept a cartilagesupport implant therein. The cartilage support implant can be flattenedor compressed to fit within the cannula 1302. In some embodiments, oneor more anchors are compressed. In some embodiments, one or more middleanchors are compressed. In some embodiments, one or more extensions arecompressed. The cartilage support implant can have a low-profiledelivery configuration. The cannula 1302 can include a distal end 1304and a proximal end 1306. The distal end 1304 can be open to allow fordelivery of the cartilage support implant. The distal end can include aneedle tip 1308.

The proximal end 1306 can be held by a user. The proximal end 1306 caninclude any feature to increase grip or usability of the delivery system1300. The delivery system 1300 can include a push rod 1312. The push rod1312 can be designed to be disposed within the cannula 1302. The pushrod 1312 can translate within the cannula 1302 to push the cartilagesupport implant from the distal end 1304 of the delivery system 1300.The delivery system 1300 can include a deployment knob 1314. Thedeployment knob 1314 can be designed to translate the push rod 1312within the cannula 1302.

FIGS. 14A-14C shows the cartilage support implant 300. The deliverysystem 1300 can be designed to deliver the first elongate body 302,followed by the second elongate body 304. The first elongate 302 can bedisposed within the delivery system 1300 for delivery. The firstelongate 302 can include the first end 306, the middle portion 308, antthe second end 310. The first elongate 302 can be disposed within thedelivery system 1300 such that the first end 306 is closer to the distalend 1304 of the delivery system 1300. The cartilage support implant 300can be coupled to a tether 320. The tether 320 can be coupled to aconnection point as describe herein. In some embodiments, the tether 320is coupled to the second end 310. In some embodiments, the tether 320 iscoupled to the middle portion 308. In some embodiments, the tether 320is coupled to the first end 306. In some embodiments, the tether 320 iscoupled directly to the struts 312, 314 of the first elongate body 302.

The needle tip 1308 can puncture the anatomical features, such as bone,tissue, or cartilage. The needle tip 1308 can be tapered to have ashorter end 1310. The user can position the distal end 1304 within thenasal valve of the patient. The user can position the distal end 1304near the nasal bone. The distal end 1304 can include one or moreradiopaque markers to enhance visibility and facilitate placement of thedistal end 1304. The distal end 1304 can be advanced to the positionwhere the first end 306 of the cartilage support implant 300 is to beplaced. The distal end 1304 can be advanced to the position where theanchors 322, 324 are to be placed. The needle tip 1308 can be rotated todirect the anchors 322, 324. The anchors 322, 344 can be designed todeploy from the shorter end 1310 of the cannula 1302.

To deploy, the deployment knob 1314 can be first advanced to expose theanchor portion of the implant. The one or more anchors align with theshort end 1310 of the needle tip 1308. To deploy the cartilage supportimplant 300, the deployment knob 1314 can be first advanced to exposethe anchor 322, 324. In some embodiments, the deployment knob 1314 canadvance the first end 306 from the distal end 1304 of the deliverysystem 1300. The first end 306 may or may not include an anchor. Thedeployment knob 1314 can be advanced distally (e.g., from a proximalposition to a distal position). In some embodiments, the deployment knob1314 can be rotated to translate the push rod 1312. Other configurationsare contemplated. The push rod 1312 can be advanced distally within thecannula 1302. The one or more anchors 322, 324 are exposed from thedistal end 1304. The middle portion 308 and the second end 310 of thecartilage support implant 300 can remain within the cannula 1302. Theanchors 322, 324 can expand as described herein. The anchors 322, 324can curve to a pre-determined shape. The anchors 322, 324 can engagetissue, bone, or cartilage as the anchors 322, 324 are expanded.

The delivery system 1300 can be retracted. The delivery system 1300 canslide over the middle portion 308 and the second end 310. The cartilagesupport implant 300 can be pulled out of the cannula 1302. The tether320 can remain attached to the cartilage support implant 300. The tether320 can allow for the removal or repositioning of the cartilage supportimplant 300. To reposition, the cannula 1302 can slides over the secondend 310 and middle portion 308. In some methods of use, as the cannula1032 slides along the cartilage support implant 300, the cannula 1302can cause the anchors 322, 324 to straighten. In some methods of use,the elongate body 302 of the cartilage support implant 300 can be pulledby the tether 320. The anchors 322, 344 are pulled into the cannula 1302by the tether 320. Other configurations for retraction are contemplated.

FIGS. 15A-15L illustrate methods of use of the cartilage support implant300 and the cartilage support delivery system 1300. FIG. 15A illustratesthe delivery system 1300 approaching the patient. The elongate body 302of the cartilage support implant 300 can be compressed within thecannula 1302. The distal end 1304 approaches the anatomy of the patient.In the illustrated example, a clear block is utilized schematically asrepresentative of the anatomy of a patient.

FIG. 15B illustrates the needle tip 1308 of the delivery system 1300penetrating the patient. The elongate body 302 of the cartilage supportimplant 300 can be compressed within the cannula 1302. The needle tip1308 can puncture through tissue, cartilage, and/or bone. The needle tip1308 can form a straight path.

FIG. 15C illustrates the first end 306 of the elongate body 302extending from the cannula 1302 of the delivery system 1300. Thedelivery system 1300 can include the push rod 1312. The push rod 1312can apply a force such that the first end 306 of the elongate body 302extends from the short end 1310 of the needle tip 1308. The first end306 of the elongate body 302 can include the first anchor 322 and thesecond anchor 324. The first anchor 322 and the second anchor 324 canextend from the cannula 1302. As the first anchor 322 and the secondanchor 324 expands, the first anchor 322 and the second anchor 324 canassume a pre-formed curved shape. The first anchor 322 and the secondanchor 324 can include a shape memory material. The first anchor 322 andthe second anchor 324 can curve outward. FIG. 15C illustrates thebeginning of the curve for the first anchor 322 and the second anchor324.

FIG. 15D illustrates the first anchor 322 and the second anchor 324deployed. The push rod 1312 can continue to apply a force until thefirst anchor 322 and the second anchor 324 are fully extended from thecannula 1302. The first anchor 322 and the second anchor 324 can assumea pre-formed curved shape. The first anchor 322 and the second anchor324 can curve back toward the proximal end of the cannula 1302. Thefirst anchor 322 and the second anchor 324 can engage tissue, cartilage,or bone. The first anchor 322 and the second anchor 324 can penetratethe surrounding anatomy. The first anchor 322 and the second anchor 324can become embedded.

FIG. 15E illustrates the cannula 1302 of the delivery system 1300retracting along the elongate body 302. The elongate body 302 of thecartilage support implant 300 can be released from within the cannula1302.

FIG. 15F illustrates the cannula 1302 of the delivery system 1300 as thecannula 1302 is removed from the body of the patient. The elongate body302 of the cartilage support implant 300 can be completely released fromwithin the cannula 1302. The struts 312, 314 can be exposed. In someembodiments, one or more extensions or middle anchors are deployed orexpanded as the cannula 1302 of the delivery system 1300 retracts. Theconnection point 326 can be released from the cannula 1302. In someembodiments, the connection point 326 is deployed or expanded as thecannula 302 of the delivery system 1300 retracts. The connection point326 can be coupled with the tether 320. The connection point 326 can bedesigned to be retained within the patient, for instance near the lowerlateral cartilage. The tether 320 can extend from the lower lateralcartilage and out of the nose of the patient.

FIG. 15G illustrates the delivery system 1300 completed removed. Thetether 320 extends from the connection point 326. In some methods ofuse, the tether 320 is removed. In some methods of use, the tether 320can be removed once the position of the elongate body 302 of thecartilage support implant 300 is verified such as through imaging. Theelongate body 302 of the cartilage support implant 300 can include anon-resorbable material such as a metal which can be radiopaque. Theelongate body 302 of the cartilage support implant 300 can be designedto be a stabilizing stent for the nasal valve. The elongate body 302 ofthe cartilage support implant 300 can be a permanent implant. Theprocess can be repeated to deploy one or more additional elongatebodies. The elongate bodies can be placed in a parallel arrangementalong the midline of a patient's nose. In some methods of use, twoelongate bodies are deployed. Each elongate body can extend from thenasal bone to the lower lateral cartilage.

FIG. 15H illustrates the needle tip 1308 of the delivery system 1300sliding along the tether 320. In some methods of use, the elongate body302 of the cartilage support implant 300 can be retrieved. In somemethods of use, the elongate body 302 of the cartilage support implant300 can be repositioned.

FIG. 15I illustrates the needle tip 1308 of the delivery system 1300penetrating the patient again. The needle tip 1308 of the deliverysystem 1300 can penetrate the patient. The elongate body 302 of thecartilage support implant 300 can be compressed by the cannula 1302. Thecannula 1302 can slide along the struts 312, 324 of the elongate body302. The struts 312, 314 can be compressed. In some embodiments, one ormore extensions or middle anchors are compressed as the cannula 1302 ofthe delivery system 1300 advances. The needle tip 1308 of the deliverysystem 1300 advances along the struts 312, 314 and toward the anchors322, 324. In some methods of use, the elongate body 302 of the cartilagesupport implant 300 can be retrieved after a period of time (e.g., oneday, one month, one year, many years, etc.). In some methods of use, theelongate body 302 of the cartilage support implant 300 can be retrievedduring the same procedure as deployment (e.g., time period of oneminute, ten minutes, twenty minutes, one hour, etc.). In someembodiments, the device is not placed adjacent to the maxillary bone.

FIG. 15J illustrates the tension applied to the tether 320. The tether320 can extend from the connection point 326. In some methods of use,the tether 320 is pulled to apply tension to the elongate body 302. Thetether 320 applies a force to the elongate body 302. The needle tip 1308of the delivery system 1300 can be near the end of the struts 312, 314when tension is applied. The needle tip 1308 of the delivery system 1300can be near the anchors 322, 324 when tension is applied.

FIG. 15K illustrates the first end 306 of the elongate body 302retracting into the cannula 1302 of the delivery system 1300. The tether320 can apply a force such that the first end 306 of the elongate body302 retracts along the deployment curve of the first end 306 of theelongate body 302. The first end 306 of the elongate body 302 caninclude the first anchor 322 and the second anchor 324. The first anchor322 and the second anchor 324 can retract into the cannula 1302. As thefirst anchor 322 and the second anchor 324 retracts, the first anchor322 and the second anchor 324 can follow a curved shape toward thecannula 1302.

FIG. 15L illustrates the cannula 1302 of the delivery system 1300 as thecannula 1302 is removed from the body of the patient. The elongate body302 of the cartilage support implant 300 can be compressed within thecannula 1302.

FIGS. 16A-16I illustrate an embodiment of a cartilage support implant1400 and a cartilage support delivery system 1500. FIG. 16A illustratesan elongate body 1402 of a cartilage support implant 1400. The cartilagesupport implant 1400 can include a plurality of elongate bodies, asdescribed herein. The implant can include two or more expandablesections. The implant can be about 0.6″ in length. Other lengths arecontemplated (e.g., about 0.1″, 0.2″ 0.3″, 0.4″, 0.5″, 0.65″, 0.7″,0.8″, 0.9″, 1.″, etc. or ranges incorporating two of the aforementionedvalues). The elongate body 1402 can include a first end 1406. In someembodiments, the first end 1406 configured to be placed near the nasalbone. The first end 1406 can include one or more anchors, as describeherein. The elongate body 1402 can include a middle portion 1408. Insome embodiments, the middle portion 1406 is configured to be placednear the upper lateral cartilage. The elongate body 1402 can include asecond end 1410. In some embodiments, the second end 1410 is configuredto be placed near the lower lateral cartilage. The cartilage supportimplant 1400 can include any feature of the cartilage support implantsdescribed herein.

The elongate body 1402 can include a first strut 1412 and a second strut1414. The first strut 1412 and a second strut 1414 can be connected by adistal curve 1416 at the second end 1410. The first strut 1412 and thesecond strut 1414 can extend from the distal curve 1416 and be parallelfor at least a portion of the length. The distal curve 1416 can form theconnection point 1426. The first strut 1412 and the second strut 1414can be separated along the length of the elongate body 1402. The twostruts 1412, 1414 can be connected by a proximal curve 1430. Theproximal curve 1416 can form the anchor 1422. The proximal curve 1416can form the first end 1406.

The anchor 1422 and/or the connection point 1426 can form a complete ornearly complete circle. The anchor 1422 and/or the connection point 1426can form an enclosed perimeter or other closed shape. The closed shapemay facilitate retention of the tether within the connection point 1426.The anchor 1422 and/or the connection point 1426 can be fixed inposition or expandable.

The elongate body 1402 can include one or more middle extensions. Theelongate body 1402 can include a first middle extension 1462 and asecond middle extension 1464. The middle extensions 1462, 1464 can bedesigned to engage tissue along the length of the elongate body 1402.The extensions 1462, 1464 can be designed to engage the upper lateralcartilage. The extensions 1462, 1464 can be disposed in the middleportion 1408 of the elongate body 1402. The extensions 1462, 1464 canincrease a dimension of the elongate body 1402. The extensions 1462,1464 can increase a width or thickness of the elongate body 1402. Theextensions 1462, 1464 can be fixed in position or expandable.

FIGS. 16B-16C illustrate an embodiment of a cartilage support deliverysystem 1500 for a cartilage support implant. The cartilage supportdelivery system 1500 can be designed to delivery any cartilage supportimplant described herein. In some embodiments, the cartilage supportdelivery system 1500 delivers one elongate body at a time. In someembodiments, the cartilage support delivery system 1500 delivers two ormore elongate body simultaneously.

The delivery system 1500 can include an inserter 1522. The inserter 1522can be solid, such as a solid needle. The inserter 1522 can be designedto accept a cartilage support implant thereon. The cartilage supportimplant can be flattened or compressed to fit onto the inserter 1522 asdescribed herein. In some embodiments, one or more anchors arecompressed. In some embodiments, one or more middle anchors arecompressed. In some embodiments, one or more extensions are compressed.In some embodiments, one or more connection points are compressed. Thecartilage support implant can have a low-profile delivery configuration.The inserter 1522 can include a distal end 1524 and a proximal end 1526.The distal end 1524 can be open or closed. The distal end 1524 caninclude a needle tip 1528.

The proximal end 1526 can be held by a user. The proximal end 1526 caninclude a handle. The proximal end 1526 can include any feature toincrease grip or usability of the delivery system 1500. The deliverysystem 1500 can include a first hook 1530 and a second hook 1532. Thefirst hook 1530 can be distal to the second hook 1532. The first hook1530 can be designed to be disposed on or coupled to the inserter 1522.The first hook 1530 can be fixed. The second hook 1532 can be designedto be disposed on or coupled to the inserter 1522. The second hook 1532can be movable. The second hook 1532 can translate relative to theinserter 1522 to compress the cartilage support implant such as theelongate body 1402 of the cartilage support implant 1400. The secondhook 1532 can translate proximally toward the proximal end 1526 tocompress the implant. The delivery system 1500 can include a deploymentknob 1534. The deployment knob 1534 can be designed to translate thesecond hook 1332 relative to the inserter 1522. FIGS. 16B-16C illustratethe delivery system 1500 including the delivery inserter, the first hookand the second hook. The implant is held via tension between the twohooks. The implant is applied with sliding knob attached to the proximalhook.

FIGS. 16D-16E illustrates the elongate body 1402 of the cartilagesupport implant 1400 and the delivery system 1500. The delivery system1500 can be designed to deliver the first elongate 1402, followed by asecond elongate body (not shown). The first elongate 1402 can bedisposed onto the delivery system 1500 for delivery. The cartilagesupport implant 1400 can be coupled to a tether 1420. The tether 1420can be coupled to the connection point 1426 as describe herein. In someembodiments, the tether 1420 is coupled to the second end 1410. In someembodiments, the tether 1420 is coupled directly to the first strut 1412and/or the second strut 1414 of the first elongate body 1402.

To compress the elongate body 1402, the anchor 1422 is coupled to thefirst hook 1530. The anchor 1422 can form an enclosed shaped designed tofit around the first hook 1530. The connection point 1426 is coupled tothe second hook 1532. The deployment knob 1534 can be coupled to thesecond hook 1532. FIG. 15D illustrates the elongate body 1402 loadedonto the first hook 1530 and the second hook 1532. The first hook 1530and the second hook 1532 hold the elongate body 1402 in the expandedconfiguration. The deployment knob 1534 can slide to apply tension tothe elongate body 1402. FIG. 15E illustrates the elongate body 1402 withtension applied by the first hook 1530 and the second hook 1532. Theimplant deforms to low profile with tension. FIG. 15D illustrates theun-tensioned state. FIG. 16E illustrates the tensioned state. The systemcan include a handle at the proximal end 1526. The handle can facilitategrip of the delivery system while tension is being applied. The systemcan include the implant, such as any implant described herein. Thedistal end can include a trocar or inserter shaft. The system caninclude retainer hooks.

FIGS. 16F-16H illustrates end views of the inserter shaft. FIG. 16Fshows the implant, the retainer and the shaft. The implant can be anycartilage support implant described herein, including cartilage supportimplant 1400. The retainer can be the first hook 1530 or the second hook1532. The shaft can be a portion of the inserter 1522 along the length.In FIG. 16F, the shaft of the inserter 1522 is cup-shaped or concave.The concave shape may facilitate retention of the implant. The retaineris T-shaped. Other shapes for the first hook 1530 and the second hook1532 are contemplated (e.g., J-shaped, S-shaped, U shaped, etc.). InFIG. 16G, the shaft of the inserter 1522 is block-shaped. The sides ofthe inserter 1522 can be rounded. The implant can be retained on a flatsurface. In FIG. 16H, the shaft of the inserter 1522 is cannulated,hollow or ring-shaped. The sides of the inserter 1522 can be rounded.The implant can be retained on a rounded surface.

FIG. 16I illustrates another embodiment of a delivery system 1600. Thecartilage support delivery system 1600 can be designed to delivery anycartilage support implant described herein. In some embodiments, thecartilage support delivery system 1600 delivers one elongate body at atime. In some embodiments, the cartilage support delivery system 1600delivers two or more elongate body simultaneously.

The delivery system 1600 can include an inserter 1642. The inserter 1642can be a hypotube or other cannulated structure. The inserter 1642 canbe designed to accept a cartilage support implant thereon. The cartilagesupport implant can be flattened or compressed to fit onto the inserter1642 as described herein. The inserter 1642 can include a distal end1624 and a proximal end 1626. The distal end 1624 can include a needletip 1628.

The proximal end 1626 can be held by a user. The delivery system 1600can include a first hook 1630 and a second hook 1632. The first hook1630 can be distal to the second hook 1632. The first hook 1630 can bedesigned to be disposed on or coupled to the inserter 1622. The firsthook 1630 can be movable. The second hook 1632 can be designed to bedisposed on or coupled to the inserter 1622. The second hook 1632 can befixed.

The first hook 1630 can translate relative to the inserter 1642 tocompress the cartilage support implant such as the elongate body 1402 ofthe cartilage support implant 1400. The first hook 1630 can translatedistally toward the distal end 1624 to compress the implant. Thedelivery system 1600 can include a deployment knob 1654. The deploymentknob 1654 can be designed to translate the first hook 1630 relative tothe inserter 1622. The deployment knob 1654 can be coupled to a pushrod1656. The pushrod 1656 can translated within the cannula of the inserter1642. The pushrod 1656 can be coupled to both the deployment knob 1654and the first hook 1630. Upon movement of the deployment knob 1654, thefirst hook 1630 can translate to apply tension to the implant. Otherconfigurations are contemplated.

It is contemplated that various combinations or subcombinations of thespecific features and aspects of the embodiments disclosed above may bemade and still fall within one or more of the inventions. Further, thedisclosure herein of any particular feature, aspect, method, property,characteristic, quality, attribute, element, or the like in connectionwith an embodiment can be used in all other embodiments set forthherein. Accordingly, it should be understood that various features andaspects of the disclosed embodiments can be combined with or substitutedfor one another in order to form varying modes of the disclosedinventions. Thus, it is intended that the scope of the presentinventions herein disclosed should not be limited by the particulardisclosed embodiments described above. Moreover, while the invention issusceptible to various modifications, and alternative forms, specificexamples thereof have been shown in the drawings and are hereindescribed in detail. It should be understood, however, that theinvention is not to be limited to the particular forms or methodsdisclosed, but to the contrary, the invention is to cover allmodifications, equivalents, and alternatives falling within the spiritand scope of the various embodiments described and the appended claims.Any methods disclosed herein need not be performed in the order recited.The methods disclosed herein include certain actions taken by apractitioner; however, they can also include any third-party instructionof those actions, either expressly or by implication. The rangesdisclosed herein also encompass any and all overlap, sub-ranges, andcombinations thereof. Language such as “up to,” “at least,” “greaterthan,” “less than,” “between,” and the like includes the number recited.Numbers preceded by a term such as “approximately”, “about”, and“substantially” as used herein include the recited numbers (e.g., about10%=10%), and also represent an amount close to the stated amount thatstill performs a desired function or achieves a desired result. Forexample, the terms “approximately”, “about”, and “substantially” mayrefer to an amount that is within less than 10% of, within less than 5%of, within less than 1% of, within less than 0.1% of, and within lessthan 0.01% of the stated amount.

1. A method for supporting a nasal valve comprising: providing a first elongate body and a second elongate body sized to reside within the nose of a patient; placing the first elongate body adjacent to a first nasal bone, wherein the first elongate body comprises a first anchor; placing the second elongate body adjacent to a second nasal bone, wherein the second elongate body comprises a second anchor; wherein the first elongate body and the second elongate body anchor within the nasal tissue and provide support to the nasal valve, wherein the implant is made of bioresorbable material.
 2. The method according to claim 1, wherein the first anchor curves between 5 and 360 degrees.
 3. The method according to claim 2, wherein the second anchor curves between 5 and 360 degrees.
 4. The method according to claim 1, wherein the first elongate body comprises an additional anchor feature along the length of the first elongate body.
 5. The method according to claim 4, wherein the additional anchor feature comprises a spike.
 6. The method according to claim 1, wherein the implant is a stabilizing stent that extends between the nasal bone and the lower lateral cartilage.
 7. The method according to claim 1, wherein the first elongate body is removable.
 8. The method according to claim 1, further comprising engaging two anchors of each elongate body with the anatomy of the patient.
 9. The method according to claim 1, further comprising a single point of anchoring.
 10. The method according to claim 1, wherein the first elongate body includes a coating to promote tissue ingrowth.
 11. The method according to claim 1, wherein the first elongate body extends along the midline prominence of the nose.
 12. The method according to claim 1, straightening the first elongate body within the nose of the patient.
 13. The method according to claim 1, trimming a length of the first elongate body while straightened. 14-20. (canceled)
 21. The method according to claim 1, wherein placing the first elongate body adjacent to the first nasal bone comprises engaging the first anchor with an upper lateral cartilage.
 22. The method according to claim 1, further comprising expanding the first anchor from a longitudinal axis.
 23. The method according to claim 1, wherein the first anchor comprises a closed shape.
 24. The method according to claim 1, wherein the first anchor abuts, but does not penetrate tissue surrounding the first nasal bone.
 25. A method for supporting a nasal valve comprising: providing a first elongate body sized to reside within the nose of a patient; placing the first elongate body adjacent to a first nasal bone, wherein the first elongate body comprises a first anchor; wherein the first elongate body anchors within the nasal tissue and provides support to the nasal valve, wherein the first elongate body is made of bioresorbable material.
 26. The method according to claim 25, wherein placing the first elongate body adjacent to the first nasal bone comprises engaging the first anchor with an upper lateral cartilage.
 27. The method according to claim 25, further comprising expanding the first anchor from a longitudinal axis. 